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Primeadine® Original Spermidine Supplement - Oxford Healthspan

Oxford Healthspan

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Support healthy aging and cellular renewal with Primeadine® Original, the scientifically formulated, wholly plant-derived spermidine supplement from Oxford Healthspan. Each serving provides 1mg of pure, bioavailable spermidine sourced from concentrated and defatted Japanese wheat germ extract — a premium source renowned for purity and potency.

Buy 3 bottles and save 5%.


Key Benefits

  • Promotes restful sleep and supports circadian rhythm balance

  • Encourages healthy hair growth and stronger nails

  • Enhances skin elasticity, hydration, and overall complexion

  • Boosts natural energy, vitality, and hormonal balance

  • Supports gut health and microbiome function

  • Promotes memory, cognition, and overall brain wellness

  • Mimics fasting benefits by stimulating autophagy

  • Helps protect against age-related cellular decline


Why Primeadine® Original?

Unlike synthetic spermidine or wheat germ oil blends, Primeadine® Original uses food-derived, defatted Japanese wheat germ extract to deliver natural spermidine and its synergistic polyamines — spermine and putrescine. These compounds, together with added prebiotic fiber (FOS), help your body recycle and produce more spermidine naturally, supporting long-term vitality and cellular rejuvenation.


Core Ingredients

Concentrated Japanese Wheat Germ Extract
Sourced from Japan’s pristine regions known for longevity, this wheat germ extract provides spermidine, spermine, and putrescine while being carefully defatted to remove omega-6 fatty acids (PUFAs) that can oxidize and cause inflammation. The result is a cleaner, more stable, and easily absorbed formula.

FOS (Fructooligosaccharide)
A prebiotic fiber derived from beetroot-based maltodextrin that nourishes spermidine-producing gut bacteria, supporting your body’s own natural spermidine production cycle.

Other Ingredients:
Plant cellulose capsule (Hypromellose), Sodium Citrate.


Nutritional Information (Per Serving)

  • Spermidine – 1mg

  • Naturally occurring polyamines – Spermine & Putrescine

  • FOS (Fructooligosaccharide) – Prebiotic fiber


How to Use

Serving Size: 3 capsules daily with liquid at mealtime.

For Long-Term Use:
Take with your last meal to activate autophagy before bedtime or with breakfast to extend the fasting benefits.

For First-Time Users:

  • Day 1: Take 1 capsule

  • Day 2: Take 2 capsules

  • Day 3: Take 3 capsules and continue this dosage if well tolerated.

If preferred, capsules can be opened and added to food or drinks below 40°C (104°F).


Free From

Synthetics, GMOs, soy, lactose, PUFAs, heavy metals, toxins, fillers, flow agents, sugar, gelatin.

Vegan • Cruelty-Free • ISO22000 Certified (Highest global food quality control standard)


Product Highlights

  • 100% plant-derived spermidine (no synthetics or additives)

  • Supports cellular renewal and longevity

  • Enhances skin, hair, and energy naturally

  • Made in Japan with strict purity and safety standards

  • Encourages natural spermidine production through gut support




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